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KMID : 0604520170430030189
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Journal of the Society of Cosmetic Scientists of Korea
2017 Volume.43 No. 3 p.189 ~ p.194
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A Study on Skin Permeability and Skin Whitening Effect of High Pressure Emulsification Processed Cosmetic )
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Jang Sue-Im
Lee So-Mi
Paik Byung-Ryol
Han Ji-Yeon
Kim Eun-Joo
Lee Hae-Kwang
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Abstract
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Skin has a strong barrier function to protect the body from external harmful factors. This strong barrier function of the skin makes for any effective substance difficult to permeate through the skin. The purpose of this study was to evaluate skin permeability of the reduced particle size by non-invasive method. The particles were prepared by high-pressure emulsification. The niacinamide prepared in a high-pressure emulsification was absorbed 1.56 times higher than the control sample. In addition, it was found from the sixth layer of keratin that was removed by tape-stripping method. This was significantly deeper penetration. The whitening efficacy of the sample containing niacinamide was evaluated before and after 6 weeks of use. The skin color was significantly improved in both pigmented area and non-pigmented area. Through this study, it was possible to visually and quantitatively confirm the permeability confirm the permeability of the reduced particle sample into skin.
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KEYWORD
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skin permeability , high-pressure emulsification , DESI-MS , skin pigmentation , clinical research
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